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SteatoSITE Overview
Data Summary
Demographics (age, sex, ethnicity, SIMD)
Co-morbidities (metabolic, cardiovascular, renal, cancers)
Laboratory tests (biochemistry, haematology)
Fibroscan results (if performed)
Liver related and co-morbid clinical events, procedures and outcomes; deaths
Medications (including statins, cardiovascular and diabetes drugs)
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Histopathology
Whole-slide scans (x20) of Haematoxylin and Eosin and Picro-Sirius Red stained sections.
NASH-CRN NAFLD Activity Score (NAS) and fibrosis stage; Steatosis, Activity, Fibrosis (SAF) scores; modified Ishak score assigned by Consultant Histopathologist panel (National liver EQA members).
Percentage steatosis and fibrosis determined by application of machine-learning pixel classifier using QuPath.
Transcriptomics
Successful RNA-seq data on 712 cases.
